Column chromatography was performed on a 230400 mesh silica gel (Fisher, Somerville, NJ) column. receptor tyrosine kinases (RTKs) have been associated with several cancers where they play a pivotal role in tumor angiogenesis.1,2Angiogenesis requires the transduction of signals from the extracellular domain D149 Dye of endothelial cells to the nucleus which is mediated by RTKs.3Solid […]